Ever since it emerged on the market I've been skeptical of this substance. I just don't trust artificial foods. Will I go so far as to claim it will cause cancer or is the equivalent of eating Agent Orange (as my most recent email claims)? No. But I know the results of the tests and I have an inherent distrust of the FDA (blaim it on my consumer health class) and their recent "hiccups" like Vioxx.
It's one of those things where if it sounds too good to be true, it probably is. Splenda isn't made from sugar, it was discovered while making a pesticide. And like pesticides, it's a chlorocarbon. Because of this, the body absorbs as little as possible. THAT is why it's adverstised as "low calorie". You only absorb about 15% of the substance. Lab rats wont even eat it!
I'm only slightly less afraid of margarine.
I think the bottom line is that we ultimately just need to cut back on sweets. That's it. We don't need to invent ways to make cookies "healthier", just maybe eat less cookies. Also use pure cane sugar, honey, or fruit as a sweetener. I know, I'm suggesting the awful, aren't I?